Title: Description of loosely bound and resonant complex quantum systems with the Gamow formalism Abstract: The description of open quantum systems is a challenge of modern physics. They demand a rigorous treatment of both the proximity of the continuum and the inter-particle correlations. Standard models, such as configuration interaction models and reaction theory, typically neglect one or the other. The use of the Gamow formalism allows to unify both aspects of these systems so as to provide a complete framework for their study. For this, bound, resonant and scattering states are used directly at the basis level, so that continuuum properties are included by construction. Correlations are taken into account by configuration mixing, with the so called Gamow Shell Model, or by a quasi-particle description, with the newly considered Gamow Hartree-Fock Bogolyoubov method. The helium, oxygen and nickel chains of nuclear isotopes will be studied as applications. Extension of the formalism outside nuclear physics will be briefly considered.